Mental focus is controlled by 4 gene switches, all 4 of which should be switched on.  

Intelligence is controlled by 4 gene switches, all 4 of which should be switched on.

Memory is controlled by 3 gene switches, all 3 of which should be switched on.

Consciousness is controlled by 4 gene switches, all 4 of which should be switched on.  None switched on leaves a person in a coma.  Less than 1 switched on makes a person not able to talk or make eye contact.  People with autism may have 2 switched on.  People with Asperger's syndrome may have 3 switched on.  People with poor social consciousness may have between 3 and 4 turned on.  These people may be super-intelligent and tend to be loners.

Gene switches can get stuck in one position.  This may be caused by saprophytic plant toxins such as, yeast toxins, slime mold toxons, and mildew toxins, in quantities of billionths of a gram.  It may be caused by synthetic, organic chemical toxins.  It may be caused by pharmaceutical drugs.

Tendencies for certain gene switching problems are sometimes inherited.  For example one family has had skin problems due to faulty switching of the toxin-absorption inhibiting genes for many generations.